How Do You Test For Hla-b27?

Why HLA B27 bool test ?

Blood test

"The HLA-B27 test is primarily ordered to help strengthen or confirm a suspected diagnosis of ankylosing spondylitis (AS), reactive arthritis, juvenile rheumatoid arthritis (JRA), or sometimes anterior uveitis. The HLA-B27 test is not a definitive test that can be used to diagnose or rule out a disorder. It is used as one piece of evidence in a constellation of signs, symptoms, and lab tests to support or rule out the diagnosis of certain autoimmune disorders, such as AS and reactive arthritis."

HLA B27 positive. What's that all about?

HLA-B27 is a gene that is passed on from your parents.

It basically means that you are more likely than others to develop certain autoimmune diseases. The most commonly associated condition is Ankylosing Spondylitis. This is a form of inflammatory arthritis that causes the spine to fuse. Other arthritic conditions are linked like Psoriatic Arthritis and Reactive Arthritis. Also, Uveitis which is a condition that causes inflammation of the eye is associated with this gene.

Just because you have it doesn't mean that you will develop any of these conditions. People who are HLA-B27 negative still develop these illnesses. If you get back pain or red/sore eyes that go blurry, see your doctor.


Ayurvedic Treatment for HLA b27 Positive?

Hi, I am suffereing with HLA B27, having a problem neck pain, back problem and other joints pain. I have this problem for the last six years and taking the pain killers on Daily basis. someone suggested me that Ayurved has a treatment for this problem, however I am unable to locate any good clinic in New Delhi. Can some one please provide me the name and place for some good ayurvedic Clinic. If you have a phone number that would be great.. Thanks in Advance Rahul

Hello Rahul... Please know certain facts yar...

1) HLA B27 is not a disease, its a gene which is present in the chromosome...

2) There are many HLA types HLA DR, HLA DW etc... Each one of us have any one of these types...

3) Ur neck pain, back problem and the joint pain is most probably a form of autoimmune arthritis - looks like an Rheumatoid or Ankylosing spondilytis..

4) The scientist have basically divided the Human beings depending on the HLA types... The one with HLA B27 type have more chances of getting such an arthritis, thats it... Its not an disease...

5) The Ayurvedic, Homeopathic, Unani people claim the cure for all the diseases which cannot be cured by the Alopathy (exception may be HIV/AIDS and Cancers, since its very well known to everyone that they cannot be cured )

6) Ofcourse I do not deny that they will not help... U can try ayurvedic treatment once.. It has helped many people, I do not say No.. But at the same time it has not helped many of them.. But whatever it is, they usually do not cause any harm..

7) Good doctor for it, I'm from bangalore, Don kno much about delhi.. Other yahoo users may help U...

Hla b 27 gene in the Air Force?

I really want to join the air force but i'm scared i will not be able to get in because of medical reasons. my dad passed down the hla b27 gene, which i don't know a lot about besides it can cause a lot of other things. i have had arthritis symptoms but have not exactly been diagnosed and same with IBS. thank you for your time and any help.

Having the HLA B27 gene doesn't mean you definitely will get arthritis. I'd assume if you haven't been officially diagnosed, it won't prevent you from joining.


Can someone explain to me what HLA-B27 is?

HLA-B27 is a gene that's passed on from one's parents.

Having this gene makes you more prone to developing specific inflammatory diseases, most commonly spondylarthropathies (spon-dil-e-arth-rop-athies), which is inflammation/arthritis of the spine.

The most common form of spondylarthropathy is Ankylosing Spondylitis (ank-a-low-zing spon-dil-itis). This is an autoimmune condition that causes inflammation or arthritis in the spine. AS causes the spine to fuse. About 90% of people with AS are positive for the HLA-B27 gene, but only a small proportion of people who are HLA-B27 positive will ever develop AS.

Being HLA-B27 isn't the whole picture. There are other things, the doctors/scientists are still yet to determine, that influence and contribute to this disease occurring.

As well as AS, there are a few other conditions that are linked with the HLA-B27 gene. These are all autoimmune diseases. They're not as tightly linked with the gene as AS is.

These are-

Reactive arthritis - a form of arthritis that occurs after an infection. Typically a gastro infection or an STD. It's usually not a long term condition.

Uveitis - often a silent disease that causes inflammation to the middle eye. It can cause blindness.

Iritis - inflammation of the iris.

Psoriatic arthritis - a form of arthritis that is nearly always linked with the skin condition, Psoriasis. It can present in a single joint, the ends of the fingers, a similar pattern to Rheumatoid Arthritis (symmetrical) or affect the spine.

Ulcerative colitis associated spondyloarthritis - a type of arthritis that affects the spine of patients with an inflammatory bowel disease.

Basically it means that you're at a higher risk than the average population for these diseases. There's nothing you can do to prevent one of these diseases occurring other than living a healthy lifestyle. The most important thing you can do is not smoke. It's a well known trigger for autoimmune diseases. If you're experiencing joint pain particularly affect the spine, fatigue, swelling, pain or redness of the eye you need to see a doctor.

Good luck.


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